There may be some routine available, I don’t know for certain.
But, to clarify, which three values are in need of change? A standard WCS entity would have a Extrusion (Normal) vector of 0,0,1
I’ll assume everything in you drawing is coplanar to the WCS’s XY plane – just that some of the 2D references have erratic properties to get the correct 2D placement. If that is correct then I would suggest using that filter showed in my previous post to pre-select all references that are essentially “upside down”. Now, invoke the MIRROR3D command, choosing the “Delete original” option.
Conceivably, you would also like to ensure all scale values are 1.0. Using a new Filter, or the Quick Select feature of the Properties Pallet, select all references that have scales not equal to 1.0. All three X, Y,Z scales can then be reset to 1 in the properties pallet.
Unless the reference geometry is symmetrical, however, the item in question may change visually from their current orientation.